Spinal Cord Research Specially in Syringomyelia

Payam Toobian

September 16, 2022

Syringomyelia is a condition that affects the spinal cord. It can result from trauma, tethered cord syndrome, or certain spinal cord tumors. However, some patients do not have an identifiable cause. In such cases, surgical procedures may be necessary to treat the condition.

MRI scan is the most reliable way to diagnose syringomyelia

Several different imaging tests may confirm a syringomyelia diagnosis. If your symptoms are consistent with the condition, your doctor may refer you to a neurologist trained in treating nervous system disorders. The neurologist will perform a medical history and a physical examination. Then, they will ask about your symptoms and recommend an MRI scan. The MRI scan is the most reliable method for diagnosing syringomyelia because it provides a clear picture of the brain and spinal cord.

Several conditions may cause syringomyelia. The most common is Chiari malformation, which occurs when tissue extends from the brain through the foramen magnum, preventing the proper flow of cerebrospinal fluid (CSF). Other causes of syringomyelia include spinal cord tumors and injuries, as well as inflammation in the area surrounding the spinal cord.

Symptoms of syringomyelia can vary significantly from person to person. Some people experience no noticeable symptoms, while others may develop severe ones. In either case, the disease can progress to significant disability. Because the symptoms of syringomyelia are so varied, you must consult your doctor as soon as you suspect that you have this condition.

In addition to an MRI scan, a doctor may recommend surgery. This procedure is effective in treating syringomyelia, but it can also cause serious complications. Chiari malformation can lead to permanent damage to the spinal cord. In addition to a poor prognosis, a delayed diagnosis can cause irreversible damage to the spinal cord.

MRI causes a reduction in syrinx cavity FA values

MRI is a powerful diagnostic tool that delineates the relevant anatomy in sagittal and axial planes. It helps determine the location and size of the syrinx cavity and the extent of cerebellar tonsillar ectopia and tonsilloma. Moreover, MRI helps exclude cystic lesions and arachnoid scarring.

MRI is also capable of detecting inflammatory changes in the spinal cord. For example, Das and Puvanendran found inflammatory changes in the cord at the location of the syrinx. These findings may be relevant to the pathophysiology of syrinx formation.

A 34-year-old woman with posttraumatic syringomyelia presented with progressive neurologic deficits. Her initial MRI revealed a subluxation at C6-C7, but subsequent scans revealed a syrinx cavity with increased intensity. Diffusely increased intensities were noted on the B, E, and F images. The CFVS was not present on the SE 2000/70 or SE 2500/80 images. The highest signal intensity was seen rostrally.

MRI is used to diagnose and treat syringomyelia, a rare condition affecting the central nervous system. Patients with syringomyelia may experience sensory loss in the upper limbs and coughing with swallowing.

MRI has improved the understanding of syringomyelia. With the widespread use of MRI, syringomyelia can now be diagnosed in children and adults. However, the pathophysiologic mechanisms underlying these findings are not fully understood.

Surgical procedures for syringomyelia reduce syrinx cavity FA values.

Surgical procedures that remove the syrinx reduce FA values in patients with syringomyelia. The FA values of the syrinx cavity are lowered at every cervical level. In a previous study, the length of the syrinx cavity was taken into account. However, it has not been shown whether the size of the syrinx cavity affects the FA/ADC values. Therefore, the study’s objective was to determine if there are any associations between the size of the syrinx cavity and FA/ADC values in patients with syringomyelia and FA/ADC values.

The most effective surgical procedure for syringomyelia is decompression surgery. This surgery will reduce the size of the syrinx cavity and restore normal spinal fluid flow. In many cases, this surgery will improve symptoms of numbness, burning pain, and weakness caused by the syrinx. However, patients who undergo surgical procedures for syringomyelia may suffer permanent nerve damage.

The cause of syringomyelia is not entirely understood. Several factors can trigger the disease, including meningitis, certain tumors in the spinal cord, or trauma. Depending on the cause of the syringomyelia, some patients have no symptoms.

Although surgical procedures for syringomyelia can reduce syrinx cavity FA levels and stabilize the condition, recurrence may require additional procedures. While the condition cannot be prevented, early diagnosis and treatment are crucial to limiting symptoms and improving the prognosis.